Use the attached demo and follow these steps: 
1. Click on the Button "open"
2. Click on the Button "insert"
3. Insert a text in the first DBMemo
4. Click in the second Memo
5. Resize the Window (the Width)
6. You'll get this Error: DBISAM Engine Error # 10030 Invalid BLOB handle for the table 'Grableistung' specified.

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 Comments

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The issue was that DBISAM was not checking to ensure that it had a valid BLOB handle before trying to open the BLOB in the TDBISAMBlobStream.Create constructor. Normally, this isn't an issue because the BLOB stream state matches the BLOB handle lifetimes in record buffers, but this is not the case with repaints in grids that create a BLOB stream in order to get the length of the BLOB.

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 Resolution

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Fixed Problem on 9/16/2021 in version 4.50 build 2

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 Products Affected

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DBISAM VCL Client-Server
DBISAM VCL Client-Server with Source
DBISAM VCL Standard
DBISAM VCL Standard with Source
DBISAM VCL Trial